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Ambiguous Genitalia

Coutii Healthy - Amibigous the genitalia or disorders of sex development (2000) is a disorder of sexual development are rare, in which the gender of the baby being unclear whether he was male or female. In infants who experience this condition, not perfect genitals so that the baby can have the mark of the male and female. In addition, the outer genitals may not match the genital organs part in sexual chromosomes or with the baby.


Amibigous the genitalia in infants can be caused by many different things, either due to chromosome abnormalities or abnormalities in hormones. Abnormalities of sexual development due to the number of chromosome usually occurs if an infant is experiencing a shortage or excess of chromosomes in the cell, such as Klinefelter Syndrome and Turner syndrome. Abnormalities of sexual development induced hormones usually associated with abnormalities in the production of hormones or sensitivity during sexual organs in the womb against the hormone.

Often amibigous genitalia does not endanger the lives of babies who suffer from the disorder. However, keep in mind that these sexual abnormalities can cause social problems, both for the babies at the time grew up as well as for families.

Causes Of Ambiguous Genitalia

The cause of the occurrence of amibigous different genitalia for baby boys and girls. Note that the main factor in determining the sex of a baby is the presence of the Y chromosome that determines male gender. If the fetal cells contained a Y chromosome, then the sex of the fetus is male. Whereas if there is no Y chromosome, then the fetus will be women.

Normally, the males will have 22 pairs of chromosomes of the body (autosomal recessive) and 1 pair of sex chromosomes or gender that is XY. While women will have 22 pairs of autosomal chromosomes and 1 pair of sex i.e. XX. Klinefelter's syndrome occurs when a man experiencing an excess of X chromosome so being XXY. While Turner syndrome happens when women lack the X chromosome so that it becomes the XO.

In addition, the sex of the baby can also be affected by fetal response against male sexual hormones, namely testosterone. Therefore, the development of the gender of a person can also be affected although mapping against the chromosomes correctly, i.e. 46 XY for males and 46 XX for females. Below is the cause of the occurrence of ambiguous genitalia or disorders of sex development (2000) which took place on the correct sex chromosome mapping, both in men and women.

The cause of the occurrence of amibigous on male genitalia, which are:
  1. Developmental disorders of the testes. The development of testes in the male fetus may be disturbed by certain factors, such as genetic abnormalities or other unknown causes.
  2. 5A-reductase enzyme deficiency. 5A-reductase enzyme plays a role in the formation of the androgen hormones that promote the development of the male genital organs. The enzyme deficiency can lead to the production of male sexual hormones become distracted and cause genital organs male is not well developed.
  3. Syndrome of insensitivitas against androgen. This condition is caused by the response of the genital organs of male fetuses that are not sensitive to the hormone androgen. Although the production of androgen hormones in the testes were not interrupted, but due to the insensitivitas against androgen, the development of organs gonads could be disrupted.
  4. Abnormalities in testosterone and testicles. The testes and male genital organs can be disrupted by various factors, both in the form of impaired the structure of organs, disorders of hormone production, as well as the disruption of hormone receptors.

The cause of the occurrence of amibigous on female genitalia, which are:

  1. The consumption of medications containing hormones androgens by pregnant women. There are some medicines that contain androgen hormones so if consumed by pregnant women can cause fetuses of women who were exposed to the hormone androgen conceived. This condition causes the genital organs of the female fetus that was being developed will contain the characteristics of male sex. In addition, the hormonal imbalance of pregnant women can also cause fetal women exposed to hormones that trigger the onset of amibigous the genitalia.
  2. The tumor. Tumors in pregnant women that result in male sexual hormones can affect the development of the genital organs of the female.
  3. Congenital adrenal hyperplasia. Congenital adrenal hyperplasia is a congenital genetic condition that appears on pregnant women. Adrenal hyperplasia causing mothers produce excess androgen hormones causing fetal abnormalities of sexual advances of women.

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